Optimal analysis of complex protein mass spectra

Optimal analysis of complex protein mass spectra.

Due to physical and chemical phenomena, a simple sample can give rise to a complex mass spectrum with many more peaks than the number of molecular species present in the sample. We link peaks within and between different spectra, and come up with an advanced analysis approach to produce reliable estimates of the molecule masses and abundances. By linking peaks, we can locate multiple-charge pea...

University of Groningen Optimal analysis of complex protein mass spectra

Optimal p-Cyclic SOR for Complex Spectra

In this work we consider the Successive Overrelaxation (SOR) method for the solution of a linear system Ax = b, when the matrix A has a block p X P partitioned p-cyclic form and its associated block Jacobi matrix Jp 1s weaJdy cyclic of index p. Following the pioneering work by Young and Varga in the 50s many researchers have considered various cases for the spectrum 0'(Jp ) and have determlned ...

Complex Gamma Ray Spectra Analysis

The gamma ray spectrometry laboratory of the University of Bucharest was designed for the analysis of low-level radioactivity samples. High efficiency shielded HPGe detectors are used. Efficiency calibration is achieved by complementing experimental calibration with Monte Carlo computation carried out using GESPECOR, also applied for the evaluation of coincidence summing corrections. Low detect...

POSITIVE AND NEGATIVE ION MASS SPECTRA OF RING - SUBSTITUTED NITROBENZENES

The 70 ev positive and negative ion mass spectra of ring-substituted nitrobenzenes were studied. The influence of the substituent group on the fragmentation modes of the molecular ions is discussed. The effect of pressure in the formation of negative ions was also studied. As expected, the ratio of fragment ions to negative molecular ions decreased with increasing pressure in ion source.